47775

Menadione (K3)

analytical standard

• 別名: メナジオン, 2-メチル-1,4-ナフトキノン, ビタミンK₃
• 実験式（ヒル表記法）: C₁₁H₈O₂
• CAS番号: 58-27-5
• 分子量: 172.18
• Beilstein: 1908453
• EC Number: 200-372-6
• MDL番号: MFCD00001681
• UNSPSCコード: 12164500
• PubChem Substance ID: 24871411

特性

• グレード: analytical standard
• 品質水準: 100
• CofA: current certificate can be downloaded
• 特徴: standard type fat soluble vitamin
• 包装: ampule of 1000 mg
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 105-107 °C (lit.)
• アプリケーション: pharmaceutical (small molecule); vitamins, nutraceuticals, and natural products
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• InChI Key: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• 遺伝子情報: human ... NQO1(1728)

詳細

詳細

Menadione (K3) is a fat-soluble vitamin precursor and catabolic product of oral phylloquinone (vitamin k1) in the intestine.

Menadione is a prothrombogenic compound and belongs to the Vitamin K class of compounds, which are necessary for the biosynthesis of prothrombin and other blood clotting factors. It is used as a model quinone in cell culture and in vivo investigations. It is obtained as a catabolic product of phylloquinone and circulating precursor of tissue menaquinone-4 in rats.

アプリケーション

Menadione (K3) may be used as an analytical reference standard for the quantification of the analyte in biological fluids using liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H317,H319,H335,H410
• 注意書き: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves