53542-U

Ascentis^® Express Peptide 160 Å ES-C18 (2.7 μm) HPLC Columns

L × I.D. 5 mm × 4.6 mm, HPLC Guard Cartridge, pkg of 3 ea

• 別名: Superficially Porous Wide Pore C18 Guard Column
• UNSPSCコード: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

特性

• 製品名: Ascentis^® Express Peptide ES C18ガードカートリッジ, 2.7 μm particle size, L × I.D. 5 mm × 4.6 mm, pkg of 3 ea
• 物質: stainless steel column
• 品質水準: 100
• 認証: suitable for USP L1
• 製品種目: Ascentis^®
• 特徴: endcapped: no
• 包装: pkg of 3 ea
• 標識化の程度: 4.6% carbon loading
• テクニック: HPLC: suitable; LC/MS: suitable; UHPLC-MS: suitable; UHPLC: suitable
• L × 内径: 5 mm × 4.6 mm
• 表面積: 90 m²/g
• Matrix: superficially porous particle
• マトリックス活性基: C18 (octadecyl) phase
• 粒径: 2.7 μm
• ポアサイズ: 160 Å
• 使用pH: 1-9
• 分離法: reversed phase

詳細

詳細

Ascentis Expresガードカラムは、Ascentis Expressカラムの極めて高い性能を保ったまま、高価な分析用カラムを物理的(ろ過)および化学的に保護します。Ascentis Expresガードカラムは、手締めだけで9000 psi(600 bar)までの圧力で連続使用できます。ガードカートリッジは、ガードカラムホルダーを流路から取り外さずに簡単に交換できます。カートリッジには、Ascentis ExpressFused-Core^®粒子が充填されています。ガードカラムホルダー(53500-U)は別にご注文ください。

アプリケーション

• Proteotypic Peptide Identification in Biosynthetic Insulin: Utilizes Ascentis^® Express Peptide ES-C18, 2.7 μm Guard Cartridge in multiplexed targeted mass spectrometry to identify proteotypic tryptic peptides of recombinant human insulin and biosynthetic insulin analogues, demonstrating high resolution and precision in peptide mapping essential for biopharmaceutical analysis (Qasem et al., 2019).


• Preclinical Pharmacokinetic Study of Thymopentin: Employs the Ascentis^® Express Peptide ES-C18, 2.7 μm Guard Cartridge for the high-resolution separation and quantitative determination of thymopentin in beagle dog blood, highlighting its application in pharmacokinetic studies and drug development (Shi et al., 2015).


• Cytochrome P450 and UDP-Glucuronosyltransferases Quantification: Features the use of Ascentis^® Express Peptide ES-C18, 2.7 μm Guard Cartridge in a targeted proteomics approach for the absolute quantification of clinically relevant enzymes, offering insights into protein expression levels critical for drug metabolism and pharmacogenomics studies (Gröer et al., 2014).


• Carotenoid Analysis in Superficially Porous Phases: Demonstrates the capability of the Ascentis^® Express Peptide ES-C18, 2.7 μm Guard Cartridge in extending the carotenoid test to new stationary phases, underlining its versatility and effectiveness in analytical chromatography for complex natural products (Lesellier, 2012).

法的情報

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Fused-Core is a registered trademark of Advanced Materials Technology, Inc.