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グレード
pharmaceutical primary standard
認証
BP
APIファミリー
hydroxychloroquine
形状
solid
シェルフライフ
limited shelf life, expiry date on the label
包装
pkg of 25 mg
メーカー/製品名
BP
保管条件
OK to freeze
色
off-white
mp
238-241 °C
溶解性
water: soluble
アプリケーション
pharmaceutical
pharmaceutical small molecule
フォーマット
neat
輸送温度
ambient
保管温度
2-8°C
SMILES記法
OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI
1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
InChI Key
JCBIVZZPXRZKTI-UHFFFAOYSA-N
遺伝子情報
human ... TLR7(51284) , TLR9(54106)
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詳細
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol (Hydroxychloroquine Sulfate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
アプリケーション
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
生物化学的/生理学的作用
ヒドロキシクロロキン硫酸塩は、抗炎症性(TNFを介する)の疾患修飾性抗リウマチ薬(DMARD)であり、ヘムポリメラーゼ阻害剤です。 マラリアの治療に使用されます。
包装
Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
その他情報
Sales restrictions may apply.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
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Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
Hydroxychloroquine Sulfate
British Pharmacopoeia, 44(12), 1000-1004 (2021)
A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Biomedical Chromatography, 32(8), e4258-e4258 (2018)
Compatibility study of hydroxychloroquine sulfate with pharmaceutical excipients using thermal and nonthermal techniques for the development of hard capsules
Journal of Thermal Analysis and Calorimetry, 421 (2019)
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