PHR1494

Pilocarpine Nitrate

Pharmaceutical Secondary Standard; Certified Reference Material

• 동의어(들): Pilocarpine nitrate salt
• 실험식(Hill 표기법): C₁₁H₁₆N₂O₂ · HNO₃
• CAS Number: 148-72-1
• Molecular Weight: 271.27
• Beilstein: 4171406
• EC Number: 205-723-7
• MDL number: MFCD00078497
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329823416
• NACRES: NA.24

속성

• Grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP 503; traceable to Ph. Eur. P1700000; traceable to USP 1539009
• API family: pilocarpine
• CofA: current certificate can be downloaded
• 포장: pkg of 500 mg
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• 저장 온도: 2-30°C
• SMILES string: O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
• InChI: 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
• InChI key: PRZXEPJJHQYOGF-GNAZCLTHSA-N
• 유전자 정보: human ... CHRM1(1128) , CHRM3(1131)

설명

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents.

애플리케이션

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

생화학적/생리학적 작용

Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.

분석 메모

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive.

안전성 정보

• 픽토그램: GHS03,GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H272,H302,H330
• 예방조치 성명서: P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
• Storage Class Code: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable