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Merck
모든 사진(1)

주요 문서

P0389

Sigma-Aldrich

Penicillinase from Bacillus cereus

lyophilized powder, 1,500-3,000 units/mg protein (using benzylpenicillin)

동의어(들):

β-Lactamase I from Bacillus cereus, β-Lactamase II, Cephalosporinase, Penicillin amido-β-lactam hydrolase

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About This Item

CAS Number:
효소 위원회 번호:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54

생물학적 소스

Bacillus sp. (Bacillus cereus)

Quality Level

형태

lyophilized powder

특이 활성도

1,500-3,000 units/mg protein (using benzylpenicillin)

구성

Protein, ~10%

기술

activity assay: suitable

응용 분야

diagnostic assay manufacturing

배송 상태

wet ice

저장 온도

2-8°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Penicillinase from Bacillus cereus has been shown to contain three distinct species when purified and examined for homogeneity by sedimentation analysis, amino-terminal analysis, and vertical acrylamide gel electrophoresis.

애플리케이션

Penicillinase can be used to reduce levels of penicillin in patients with severe penicillin reactions.
Used in the production of penicillin.
Used in the production of penicillin. Penicillinase from Bacillus cereus has been used in a comparison study with penicillinase from Bacillus subtillis where the Michaelis constant, shape of the Ph/activity curve and immunological properties were shown to be significantly different.

생화학적/생리학적 작용

Penicillinase specifically catalyzes the hydrolysis of β-lactam ring of penicillin.

단위 정의

One unit will hydrolyze 1.0 μmole of indicated substrate per min at pH 7.0 at 25 °C. Sold as benzylpenicillin units. This International Unit (using benzylpenicillin as substrate) is approximately equal to 600 Levy or 75 Pollock units.

물리적 형태

Lyophilized powder containing phosphate and citrate buffer salts

분석 메모

Protein determined by biuret.

억제제

제품 번호
설명
가격

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Cristian Piras et al.
Chemical science, 13(6), 1746-1758 (2022-03-15)
Large-scale population screening for early and accurate detection of disease is a key objective for future diagnostics. Ideally, diagnostic tests that achieve this goal are also cost-effective, fast and easily adaptable to new diseases with the potential of multiplexing. Mass
Junichiro Marui et al.
Journal of bioscience and bioengineering, 110(1), 8-11 (2010-06-15)
Aspergillus oryzae penicillin biosynthetic genes were clustered. The penicillin production was positively regulated by VeA, a global gene regulator required for transcriptional expression of the penicillin biosynthetic genes. Overexpression of the biosynthetic genes by a strong promoter yielded a greater
Anaphylactic shock after therapy with penicillinase.
A L HYMAN
Journal of the American Medical Association, 169(6), 593-594 (1959-02-07)
A Comparison of the Properties of Penicillinase produced by Bacillus subtilis and Bacillus cereus with and without Addition of Penicillin
Manson, E., et al.
Microbiology, 11, 493-505 (1954)
M A van Opstal et al.
Journal of pharmaceutical and biomedical analysis, 8(1), 49-60 (1990-01-01)
An automated assay for the determination of penicillin in formulations suitable for use in pharmaceutical quality control is presented. The method is based on the classical iodometric penicillin assay which is incorporated in a flow injection analysis (FIA) system. The

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