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Sigma-Aldrich

Glycol Chitosan Methacrylate

Degree of methacrylation ∼45%

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Synonym(s):
Chitosan hydrogel, Crosslinkble chitosan, Glycol chitosan, Methacrylated glycol chitosan
Linear Formula:
[C14H25NO8]n [C10H17NO6]m

Quality Level

form

powder

color

white to light yellow, light brown

suitability

conforms to structure for NMR

storage temp.

2-8°C

Application

Glycol chitosan is soluble at neutral pH and possesses potentially useful biological properties such as good biocompatibility accelerate wound healing, and antimicrobial properties, and it is less toxic and provide to stimulates chondrocyte growth at low concentrations. Methacrylated glycol chitosan is photo- and thermally cross-linkable and is used as a precursor for the preparation of hydrogels used in biomedical applications including drug delivery, tissue engineering, and 3D bioprinting.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Evaluation of the Properties of Soluble Chitosan and Chitosan Microspheres
Carreno-Gomez, B.; Duncan, R
International Journal of Pharmaceutics, 148 (2), 231-240 (1997)
Brian G Amsden et al.
Biomacromolecules, 8(12), 3758-3766 (2007-11-23)
Glycol chitosan is a derivative of chitosan that is soluble at neutral pH and possesses potentially useful biological properties. With the goal of obtaining biocompatible hydrogels for use as tissue engineering scaffolds or drug delivery depots, glycol chitosan was converted
K Y Lee et al.
Biomaterials, 16(16), 1211-1216 (1995-11-01)
Chitosan was selectively N-acylated with various carboxylic anhydrides, e.g., acetic, propionic, n-butyric, n-valeric and n-hexanoic anhydrides, in the presence of methanol. The degree of N-acylation of about 20-50% was obtainable without occurrence of gelation by using carboxylic anhydrides of 0.3-1.2
Eun Seok Ko et al.
Carbohydrate polymers, 245, 116496-116496 (2020-07-29)
Hydrogel systems that show self-healing ability after mechanical damage are receiving increasing attention. However, self-healing hydrogels suitable for biomedical applications are limited owing to complex preparation methods. Furthermore, few studies have demonstrated the self-healing property of ferrogels. In this study
Jobanpreet Dhillon et al.
Journal of biomedical materials research. Part A, 107(3), 571-585 (2018-11-06)
Cell-based therapies involving the injection of adipose-derived stem/stromal cells (ASCs) within rationally designed biomaterials are a promising approach for stimulating angiogenesis. With this focus, the current work explored the effects of incorporating integrin-binding RGD or IKVAV peptides within in situ-gelling

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