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A75633

Sigma-Aldrich

2-Amino-3-methylpyridine

95%

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Synonym(s):
2-Amino-3-picoline
Empirical Formula (Hill Notation):
C6H8N2
CAS Number:
Molecular Weight:
108.14
Beilstein/REAXYS Number:
107892
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

assay

95%

form

solid

refractive index

n20/D 1.5823 (lit.)

bp

221-222 °C (lit.)

mp

29-31 °C (lit.)

density

1.073 g/mL at 25 °C (lit.)

SMILES string

Cc1cccnc1N

InChI

1S/C6H8N2/c1-5-3-2-4-8-6(5)7/h2-4H,1H3,(H2,7,8)

InChI key

RGDQRXPEZUNWHX-UHFFFAOYSA-N

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1 of 4

This Item
A75684P42053662720
vibrant-m

A75633

2-Amino-3-methylpyridine

vibrant-m

A75684

2-Amino-5-methylpyridine

vibrant-m

P42053

3-Methylpyridine

vibrant-m

662720

3-Bromo-2-methylpyridine

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

100

bp

221-222 °C (lit.)

bp

227 °C (lit.)

bp

144 °C (lit.)

bp

-

mp

29-31 °C (lit.)

mp

76-77 °C (lit.)

mp

−19 °C (lit.)

mp

-

refractive index

n20/D 1.5823 (lit.)

refractive index

-

refractive index

n20/D 1.504 (lit.)

refractive index

n20/D 1.5604

form

solid

form

crystals

form

-

form

solid

pictograms

CorrosionSkull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 2

flash_point_f

244.4 °F - closed cup

flash_point_c

118 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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2-Aminopyridine

3-Methylpyridine 99%

Sigma-Aldrich

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3-Methylpyridine

3-Picolylamine ≥99%

Sigma-Aldrich

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T G Altuntas et al.
Xenobiotica; the fate of foreign compounds in biological systems, 27(11), 1103-1111 (1997-12-31)
1. The effects of various potential inhibitors, activators and inducers on the metabolism of the comutagen 2-amino-3-methylpyridine (2A3MP) by rabbit hepatic microsomes and S9 supernatants have been studied. 2. The 1-N-oxidation of 2A3MP to 2-amino-3-methylpyridine-1-N-oxide (2A3M-PNO) was inhibited by 2,4-dichloro-6-phenylphenoxyethylamine
T G Altuntas et al.
Anticancer research, 17(5A), 3485-3491 (1997-12-31)
The metabolism of the comutagen 2-amino-3-methylpyridine has been studied in vitro using rat and rabbit hepatic preparations. 2-Amino-3-methylpyridine-N-oxide, 2-amino-3-hydroxymethylpyridine and 2-amino-5-hydroxy-3-methylpyridine were formed by both rat and rabbit hepatic preparations. No evidence was obtained for the formation of the corresponding
Cengiz Yenikaya et al.
Journal of enzyme inhibition and medicinal chemistry, 26(1), 104-114 (2010-09-24)
Two novel proton transfer compounds were prepared between 2,4-dichloro-5-sulphamoylbenzoic acid (lasamide) (Hsba) and ethylenediamine (en), namely ethane-1,2-diaminium 2,4-dichloro-5-sulphamoylbenzoate (1), and also between Hsba and 2-amino-3-methylpyridine (2-amino-3-picoline) (amp), namely 2-amino-3-methylpyridinium 2,4-dichloro-5-sulphamoylbenzoate (2). All these were characterised by elemental, spectral (IR and
T G Altuntas et al.
Anticancer research, 17(6D), 4479-4482 (1998-03-12)
The metabolism of 2-amino-3-methylpyridine (2A3MP) in vitro has been investigated using the rat, rabbit, dog, marmoset, guinea pig and hamster hepatic microsomes and S9 supernatants (10,000 g fraction). Species differences were observed in the in vitro formation of 2-amino-3-methylpyridine-N-oxide (2A3MPNO)
J W Gorrod et al.
European journal of drug metabolism and pharmacokinetics, 22(4), 341-344 (1998-03-26)
The in vitro metabolism of 2-hydroxylamino-3-methylpyridine has been investigated using arochlor 1254 pretreated rat S9 mixtures. 2-Hydroxylamino-3-methylpyridine is rapidly converted to the parent amine 2-amino-3-methylpyridine. No further oxidation products of 2-hydroxylamino-3-methylpyridine (i.e. nitroso or nitro) were detected under the HPLC

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