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472476

Sigma-Aldrich

Chloroform

contains amylenes as stabilizer, ACS reagent, ≥99.8%

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Synonym(s):
Methylidyne trichloride, Trichloromethane
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
Molecular Weight:
119.38
Beilstein/REAXYS Number:
1731042
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.04

grade

ACS reagent

Quality Level

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99.8%

form

liquid

contains

amylenes as stabilizer

impurities

Acetone and aldehyde, passes test
Acid and chloride, passes test
Free chlorine (Cl), passes test
≤0.03% (water)

evapn. residue

0.001%

color

APHA: ≤10

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.48 g/mL at 25 °C
1.492 g/mL at 25 °C (lit.)

cation traces

Pb: ≤0.05 ppm

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

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1 of 4

This Item
319988480150437581
vibrant-m

472476

Chloroform

Essential Grade
vibrant-m

319988

Chloroform

Essential Grade
vibrant-m

480150

Chloroform

-
vibrant-m

437581

Chloroform

-
assay

≥99.8%

assay

≥99.8%

assay

≥99.8%

assay

≥99.8%

grade

ACS reagent

grade

ACS reagent

grade

ACS reagent

grade

ACS reagent

form

liquid

form

liquid

form

liquid

form

liquid

vapor density

4.1 (vs air)

vapor density

4.1 (vs air)

vapor density

4.1 (vs air)

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

Application

Chloroform was used in the process for isolation of RNA from yeast.
It may be used in the following processes:
  • Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
  • Preparing phospholipid solutions.
  • As a solvent in the photolysis reaction of ruthenium complexes.
  • Solvent for recrystallization.
  • Reference compound to detect the presence of chloroform in tobacco smokes.
  • Extractant in solvent extraction process.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


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A Simple RNA Preparation Procedure from Yeast for Northern Blot Using Hot Phenol.
Wei Y.
Bio-protocol, 2(12) (2012)
Systematic studies on the breakdown of p,p'-DDT in tobacco smokes. Presence of methyl chloride, dichloromethane, and chloroform in tobacco smokes.
Chopra NM and Sherman LR.
Analytical Chemistry, 44(6), 1036-1038 (1972)
The affinity of two antimicrobial peptides derived from bovine milk proteins for model lipid membranes.
Barzyk W, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 343(1), 104-110 (2009)
Kinetics and Mechanism of the Photooxidation of Bis (bipyridine) dichlororuthenium (II) and the Photoreduction of Bis (bipyridine) dichlororuthenium (III) in Chloroform.
Sathiyabalan S and Hoggard PE.
Inorganic Chemistry, 34(18), 4562-4571 (1995)
Eagleson M.
Concise Encyclopedia Chemistry, 216-216 (1994)

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