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30906

Sigma-Aldrich

Castor Oil, Ethoxylated

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Synonym(s):
Cremophor® ELP, Kolliphor® ELP, PEG-35 castor oil, Polyoxyl-35 castor oil
CAS Number:
MDL number:
NACRES:
NA.25

description

non-ionic

Quality Level

form

paste

impurities

alkalinity, complies
≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only)
≤0.1% oleic acid
≤0.1% palmitic acid
≤0.2% sulfated ash (verfied on random samples only)
≤0.20% ricinoleic acid
≤0.5% water
≤1 ppm ethylene oxide (verfied on random samples only)
≤1.0% free fatty acids
≤10 ppm dioxan (verfied on random samples only)
≤10 ppm heavy metals (verfied on random samples only)
≤620 ppm diethylene glycol (verfied on random samples only)
≤620 ppm ethylene glycol (verfied on random samples only)

ign. residue

≤0.2%

pH

5.0-7.0 (1 g/10 mL in H2O)

viscosity

600-750 mPa.s(25 °C)

acid value

≤2.0 mg KOH/g

hydroxyl value

65‑78 mg KOH/g

iodine value

25‑35 g/100g

saponification value

65‑70 mg KOH/g

cation traces

K: ≤15 ppm

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

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C5135PHR2972PHR2965
Sigma-Aldrich

30906

Castor Oil, Ethoxylated

Sigma-Aldrich

C5135

Castor Oil, Ethoxylated

Supelco

PHR2972

Castor Oil

Supelco

PHR2965

Plastic Additive 16

viscosity

600-750 mPa.s(25 °C)

viscosity

-

viscosity

-

viscosity

-

Quality Level

100

Quality Level

200

Quality Level

100, 300

Quality Level

300

description

non-ionic

description

non-ionic

description

-

description

-

cation traces

K: ≤15 ppm

cation traces

-

cation traces

-

cation traces

-

impurities

alkalinity, complies, ≤0.1% oleic acid, ≤0.2% sulfated ash (verfied on random samples only), ≤0.5% water, ≤1.0% free fatty acids, ≤10 ppm heavy metals (verfied on random samples only), ≤620 ppm ethylene glycol (verfied on random samples only), ≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only), ≤0.20% ricinoleic acid, ≤10 ppm dioxan (verfied on random samples only)

impurities

-

impurities

-

impurities

-

Application

Castor Oil, Ethoxylated is used to emulsify and solubilize oils and other water-insoluble substances. Similar to Castor Oil, Ethoxylated but with lower water content and differences in viscosity.

Analysis Note

relative density D (25/25) 1.05-1.06

Legal Information

Cremophor is a registered trademark of BASF SE
Kolliphor is a registered trademark of BASF

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

494.6 °F - Not applicable

flash_point_c

257 °C - Not applicable


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Nuhad K Ibrahim et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 8(5), 1038-1044 (2002-05-15)
ABI-007 is a novel Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. The absence of Cremophor EL may permit ABI-007 to be administered without the premedications used routinely for the prevention of hypersensitivity reactions. Furthermore, this novel formulation permits a higher paclitaxel
Yukako Ito et al.
Journal of drug targeting, 13(6), 383-390 (2005-11-10)
Interferon alpha (IFN-alpha), patch preparations composed of three layers, water-insoluble backing layer, drug containing layer with absorption enhancer and surface layer containing pH-dependent polymer were prepared. As absorption enhancer, three surfactants, Gelucire44/14 (Lauroyl macrogol-32 glycerides), Labrasol (Caprylocaproyl macrogol-8 glycerides) and
Shu Yu et al.
Vaccine, 30(36), 5425-5436 (2012-06-20)
Oil-in-water emulsions are potent human adjuvants commonly used in effective pandemic influenza vaccines; however, such emulsions that can induce both Th1-biased systemic immune responses and strong mucosal immune responses via an easy method of administration are lacking. To address this
Eiki Goto et al.
Ophthalmology, 109(11), 2030-2035 (2002-11-05)
We developed low-concentration homogenized castor oil eye drops for the treatment of patients with noninflamed obstructive meibomian gland dysfunction (MGD), a major cause of lipid-deficiency dry eye, and assessed the safety, stability, and efficacy of the eye drops. Randomized, double-masked
Yun-Seok Rhee et al.
Archives of pharmacal research, 30(1), 114-123 (2007-03-03)
The aim of this study was to develop an aqueous parenteral formulation containing itraconazole (ITZ) using an o/w microemulsion system. A mixture of benzyl alcohol and medium chain triglyceride (3/1) was chosen as the oil phase. Pseudoternary phase diagrams of

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