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62035

Sigma-Aldrich

Kolliphor® P 407

oxyethylene 71.5-74.9 %

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Synonym(s):
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Lutrol® F 127, Poloxamer 407
CAS Number:
9003-11-6
MDL number:
MFCD00082049
NACRES:
NA.25

composition

oxyethylene, 71.5-74.9%

Quality Level

100

impurities

≤0.25% ethylene glycol and diethylene glycol
≤0.4% total ash
≤0.75% water
≤1 ppm ethylene oxide
≤2 ppm arsenic traces
≤20 ppm heavy metals
≤5 ppm dioxan
≤5 ppm propylene oxide
50-125 ppm butylhydroxytoluene

ign. residue

≤0.30%

color

APHA: ≤120, 50/50 in CH3OH

pH

5.0-7.5 (1:40 in H2O)

solubility

10%, clear, colorless

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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1 of 4

This Item
K48941575950246
Kolliphor® P 407 oxyethylene 71.5-74.9 %

Sigma-Aldrich

62035

Kolliphor® P 407

Kolliphor® P 188 solid

Sigma-Aldrich

K4894

Kolliphor® P 188

Kolliphor® P 188

Sigma-Aldrich

15759

Kolliphor® P 188

Kolliphor® P 407 micro

Sigma-Aldrich

50246

Kolliphor® P 407 micro

solubility

10%, clear, colorless

solubility

-

solubility

-

solubility

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

composition

oxyethylene, 71.5-74.9%

composition

-

composition

oxyethylene, 79.9-83.7%

composition

oxyethylene content, 71.5-74.9%

ign. residue

≤0.30%

ign. residue

-

ign. residue

≤0.30%

ign. residue

≤0.30%

color

APHA: ≤120, 50/50 in CH3OH

color

-

color

APHA: ≤120, 50/50 in CH3OH

color

APHA: ≤120

Application

Kolliphor P 407 has been widely used as a thickening agent and gel binder.
This research grade product is intended for use in R&D and development only.

Other Notes

The Kolliphor grades are poloxamers from the extensive line of Pluronic block copolymers.

Legal Information

Kolliphor is a registered trademark of BASF
Lutrol is a registered trademark of BASF SE

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Céline Durand-Gasselin et al.
Langmuir : the ACS journal of surfaces and colloids, 27(20), 12329-12335 (2011-09-29)
Aggregation of thermosensitive polymer-coated gold nanoparticles was performed in aqueous solution in the presence of a triblock copolymer poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic P123, PEO(20)-PPO(68)-PEO(20)). The gold nanoparticles, AuNPs, which are covered by thermosensitive statistical copolymers poly(EO(x)-st-PO(y)), aggregate when the
Wei Xu et al.
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The aim of this study was to construct novel targeting polymeric micelles. Folate-Poly (ethylenimine)-Pluronic copolymers were synthesized. A paclitaxel (PTX)-loaded mixed micelles consisting of Folate-Poly (ethylenimine)-Pluronic and Pluronic L121 copolymers have been developed. The mixed micelles showed nano-sized spherical morphology.
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Colloids and surfaces. B, Biointerfaces, 97, 101-108 (2012-05-23)
In this study, curcumin (Cur) loaded mixed micelles (Cur-PF), composed of Pluronic P123 (P123) and Pluronic F68 (F68), was prepared using the thin-film hydration method and evaluated in vitro. The preparation process was optimized with a central composite design (CCD).
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Biomaterials, 34(5), 1581-1590 (2012-11-14)
The metastasis of breast cancer is the leading cause of cancer death in women, and the lung is a common location of a secondary tumor that has metastasized from the primary source tumor. In this work, an attempt to simultaneously
A Kiwilsza et al.
Journal of microencapsulation, 30(1), 21-27 (2012-06-09)
Mesoporous material SBA-15 of hexagonal structure was synthesised and its usefulness as a carrier for a poorly soluble drug--lacidipine (LA)--was tested. The source of silica was tetraethyl orthosilicate (TEOS) and the structure ordering agent was non-ionic surfactant Pluronic P123. SBA-15
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