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Sigma-Aldrich

Kolliphor® P 407 micro

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Synonym(s):
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Lμtrol® micro 127, Poloxamer 407, micronized
CAS Number:
MDL number:
NACRES:
NA.25

mol wt

~9840-14600 g/mol

Quality Level

composition

oxyethylene content, 71.5-74.9%

impurities

≤0.25% ethylene glycol and diethylene glycol
≤0.4% total ash
≤0.75% water
≤1 ppm ethylene oxide
≤2 ppm arsenic
≤20 ppm heavy metals
50-125 ppm butylhydroxytoluene

ign. residue

≤0.30%

color

APHA: ≤120

particle size distribution

, coeff var ≤10% (residue, No. 140 USS)
, coeff var ≤50% (residue, No. 270 USS)

pH

5.0-7.5(1:10)
5.0-7.5(1:40)

suitability

complies for Infrared spectrum

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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1 of 4

This Item
15759K489462035
Kolliphor® P 188

Sigma-Aldrich

15759

Kolliphor® P 188

Kolliphor® P 188 solid

Sigma-Aldrich

K4894

Kolliphor® P 188

Kolliphor® P 407 oxyethylene 71.5-74.9 %

Sigma-Aldrich

62035

Kolliphor® P 407

impurities

≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤0.75% water, ≤1 ppm ethylene oxide, ≤2 ppm arsenic, ≤20 ppm heavy metals, 50-125 ppm butylhydroxytoluene

impurities

≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤1 ppm ethylene oxide, ≤1.0% water, ≤2 ppm arsenic traces, ≤20 ppm heavy metals, ≤5 ppm dioxan, ≤5 ppm propylene oxide, 50-150 ppm butylhydroxytoluene

impurities

-

impurities

≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤0.75% water, ≤1 ppm ethylene oxide, ≤2 ppm arsenic traces, ≤20 ppm heavy metals, ≤5 ppm dioxan, ≤5 ppm propylene oxide, 50-125 ppm butylhydroxytoluene

suitability

complies for Infrared spectrum

suitability

-

suitability

-

suitability

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

composition

oxyethylene content, 71.5-74.9%

composition

oxyethylene, 79.9-83.7%

composition

-

composition

oxyethylene, 71.5-74.9%

ign. residue

≤0.30%

ign. residue

≤0.30%

ign. residue

-

ign. residue

≤0.30%

Application

The Kolliphor® P grades are poloxamers from the extensive line of Pluronic® block copolymers. They are widely used as a thickening agent and gel binder.

Analysis Note

residual solvents (GLC-HS)
1,4-dioxane ≤5 ppm, ethylene glycol ≤620 ppm ( verified on random samples only)

Other Notes

average molecular weight/mass 9840-14600 g/mol; average molecular mass 10000-14600 g/mol

Legal Information

Kolliphor is a registered trademark of BASF
Lμtrol is a registered trademark of BASF SE
Pluronic is a registered trademark of BASF

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Mi Mi Wan et al.
Journal of colloid and interface science, 377(1), 497-503 (2012-04-18)
New concept on the promotion of immobilization and catalytic activity of enzyme on mesoporous silica through template micelles is proposed and realized in this paper. Proper P123 templates are controllable retained in the as-synthesized SBA-15, not only to anchor the
Laurien Buitinga et al.
Clinical and experimental rheumatology, 29(5), 783-789 (2011-10-04)
The Time Trade-Off (TTO) is an instrument used for valuing health-related quality of life. This study evaluated the test-retest reliability of a computer TTO in rheumatoid arthritis (RA), and compared the computer with the interview TTO regarding feasibility and agreement.
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report

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