Skip to Content
MilliporeSigma
All Photos(1)

Documents

90718

Sigma-Aldrich

Fluorescein isothiocyanate–dextran

average Mw 70,000

Synonym(s):

FITC–Dextran 70, FITC–Dextran

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
60842-46-8
MDL number:
MFCD00131092
UNSPSC Code:
12352201
NACRES:
NA.32

biological source

synthetic

conjugate

FITC conjugate

form

powder or crystals

mol wt

average Mw 70,000

extent of labeling

0.001-0.020 mol/mol FITC glucose

fluorescence

λex 493 nm; λem 520 nm±5 nm in 0.1 M Tris pH 8.0

application(s)

cell analysis

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Fluorescein isothiocyanate–dextran is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. Fluorescein isothiocyanate–dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform., however, it dissolves in DMSO, formamide, and a few other polar organic solvents.

application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.
Fluorescein isothiocyanate–dextran has an application of cell analysis, Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals. FITC-dextrans are primary source of studying permeability and transport in cells and tissues and can also be a tool for permeability studies of other materials.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jun-Ichi Takino et al.
Scientific reports, 11(1), 2959-2959 (2021-02-05)
Advanced glycation end-products (AGEs) are formed by the non-enzymatic reaction of sugars and proteins. Among the AGEs, glyceraldehyde-derived toxic AGEs (TAGE) are associated with various diseases, including diabetic complications such as diabetic retinopathy (DR). The risk of developing DR is
Sandra Dittmar et al.
Journal of virology, 82(22), 11273-11282 (2008-09-05)
In order to analyze whether measles virus (MV) is transported via transmigrating leukocytes across endothelial barriers or whether virus spreads via infection of endothelial cells and basolateral release, we investigated the migratory behavior of infected human primary T lymphocytes across
Hu Huang et al.
PloS one, 6(6), e21411-e21411 (2011-07-07)
VEGFR1 and 2 signaling have both been increasingly shown to mediate complications of ischemic retinopathies, including retinopathy of prematurity (ROP), age-related macular degeneration (AMD), and diabetic retinopathy (DR). This study evaluates the effects of blocking VEGFR1 and 2 on pathological
Gabor Eros et al.
Arthritis research & therapy, 11(2), R43-R43 (2009-03-20)
Phosphatidylcholine and phosphatidylcholine-derived metabolites exhibit anti-inflammatory properties in various stress conditions. We hypothesized that dietary phosphatidylcholine may potentially function as an anti-inflammatory substance and may decrease inflammatory activation in a chronic murine model of rheumatoid arthritis (collagen-induced arthritis). The experiments

Articles

FITC-labelled polysaccharides

Explore FITC-labelled polysaccharides and their properties, including impact of molecular weight on molecule dimensions.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service