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G9885

Sigma-Aldrich

α1-Acid Glycoprotein from human plasma

≥99% (agarose gel electrophoresis)

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Synonym(s):
AGP, Orosomucoid
CAS Number:
MDL number:
NACRES:
NA.32

biological source

human plasma

assay

≥99% (agarose gel electrophoresis)

form

powder

technique(s)

ELISA: suitable

impurities

HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... ORM1(5004)

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A9511A1887A1653
vibrant-m

A9511

Albumin from human serum

vibrant-m

A1887

Albumin from human serum

vibrant-m

A1653

Albumin from human serum

assay

≥99% (agarose gel electrophoresis)

assay

≥97% (agarose gel electrophoresis)

assay

≥96% (agarose gel electrophoresis)

assay

≥96% (agarose gel electrophoresis)

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable, tissue culture: suitable, western blot: suitable

technique(s)

ELISA: suitable, tissue culture: suitable, western blot: suitable

technique(s)

ELISA: suitable, tissue culture: suitable, western blot: suitable

Gene Information

human ... ORM1(5004)

Gene Information

human ... ALB(213)

Gene Information

human ... ALB(213)

Gene Information

human ... ALB(213)

UniProt accession no.

P02763

UniProt accession no.

P02768

UniProt accession no.

P02768

UniProt accession no.

P02768

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.

Application

α1-Acid glycoprotein from human plasma has been used:
  • as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
  • to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
  • to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors

Biochem/physiol Actions

α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.

Preparation Note

Purified from Cohn Fraction VI

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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