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S3386

Sigma-Aldrich

Sorbitan sesquioleate

nonionic surfactant

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Synonym(s):
Arlacel® 83, Span® 83
CAS Number:
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

biological source

corn

vapor pressure

0.81 psi ( 20 °C)

form

liquid

refractive index

n20/D 1.478 (lit.)

density

0.989 g/mL at 25 °C (lit.)

functional group

ester

lipid type

oils

shipped in

ambient

storage temp.

room temp

SMILES string

OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C2OC[C@H](O)[C@H]2O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/3C18H34O2.2C6H12O5/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(8)6-5(10)4(9)2-11-6/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-10H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1

InChI key

SPFRYHCSFBFNTR-RKGWDQTMSA-N

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1 of 4

This Item
W302805W302902388920
vibrant-m

S3386

Sorbitan sesquioleate

vibrant-m

W302805

Sorbitan monostearate

vibrant-m

W302902

D-Sorbitol

vibrant-m

388920

Sorbitan monopalmitate

functional group

ester

functional group

-

functional group

-

functional group

-

Quality Level

200

Quality Level

400

Quality Level

400

Quality Level

200

refractive index

n20/D 1.478 (lit.)

refractive index

-

refractive index

-

refractive index

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

-

General description

Sorbitan sesquioleate (SSO) is a sorbitol derivative emulsifier. It is a common emulsifier component in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions and topical retinoids.

Biochem/physiol Actions

Sorbitan sesquioleate is useful as a stabilizing agent in polymerization process to produce spherical acrylamide beads. It has been used in many topical agents. SSO have recently been implicated in allergic dermatitis.

Other Notes

Fatty acid composition: Oleic acid (C18:1) approx. 70%; balance primarily palmitic acid (C16:0), stearic acid (C18:0) and linoleic acid (C18:2).

Legal Information

Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Sorbitan sesquioleate as an allergen.
D I Orton et al.
Contact dermatitis, 44(3), 190-191 (2001-02-24)
S Fukanoki et al.
Avian diseases, 44(4), 869-873 (2001-02-24)
The relationship between the antigen release from formulations in vitro and the antibody response after administration of water-in-oil-in-water (W/O/W) emulsion vaccines containing Haemophilus paragallinarum (Hpg) was studied in chickens. Increases of sorbitan sesquioleate volume in the formulation led to slower
Sorbitan sesquioleate.
Mari Paz Castanedo-Tardan et al.
Dermatitis : contact, atopic, occupational, drug, 19(4), E22-E23 (2008-08-05)
The Validity of Patch Testing
Lachapelle JM, et al.
Patch Testing Tips, 49(4), 37-61 (2014)
Contact urticaria syndrome from sorbitan sesquioleate in a corticosteroid ointment.
M Hardy et al.
Contact dermatitis, 32(6), 360-361 (1995-06-01)

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