Skip to Content
MilliporeSigma
All Photos(3)

Key Documents

View All Documentation

S6635

Sigma-Aldrich

Span® 20

greener alternative

Synonym(s):

Sorbitan laurate, Sorbitan monolaurate

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

CAS Number:
1338-39-2
EC Number:
215-663-3
MDL number:
MFCD00005365
UNSPSC Code:
12161900
PubChem Substance ID:
24899716
NACRES:
NA.25

description

non-ionic

Quality Level

200

mol wt

346.47 g/mol

greener alternative product characteristics

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

concentration

≥44% (GC)

greener alternative category

, Aligned

SMILES string

CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1

InChI key

LWZFANDGMFTDAV-WYDSMHRWSA-N

Related Categories

General description

Span 20 is a co-surfactant.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is 100% bio-based non-ionic surfactant, thus aligns with "Use of Renewable Feedstocks" and belongs to "12 principles aligned" category of our greener alternatives.

Application

Span 20 has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.

Other Notes

Fatty acid composition: Lauric acid (C12:0) ≥ 44%; balance primarily myristic (C14:0), palmitic (C16:0) and linolenic (C18:3) acids.

Legal Information

Span is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

>300.2 °F - closed cup

flash_point_c

> 149 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Gabriela Calderó et al.
Journal of colloid and interface science, 353(2), 406-411 (2010-10-26)
Formation of polymeric O/W nano-emulsions has been studied in the water/polyoxyethylene 4 sorbitan monolaurate/ethylcellulose solution system by the phase inversion composition (PIC) method. These nano-emulsions were used for the preparation of nanoparticles by solvent evaporation. Composition variables such as O/S
Orapan Paecharoenchai et al.
Journal of drug targeting, 20(9), 783-792 (2012-08-31)
Non-ionic surfactant-based vesicles (niosomes) composed of non-ionic surfactants (i.e., Tween and Span) and cholesterol were formulated, and their turbidity and particle size assayed. The most appropriate niosomes formulation was mixed with novel synthesized spermine-based cationic lipids to prepare cationic niosomes
Yuji Komizu et al.
Bioorganic & medicinal chemistry letters, 21(13), 3962-3965 (2011-06-03)
Markedly inhibitory effects of hybrid liposomes (HL-n) composed of 90 mol% L-α-dimyristoylphosphatidylcholine (DMPC) and 10 mol% polyoxyethylene(n) dodecyl ethers on the growth of adult T-cell leukemia cells were obtained for the first time. It is noteworthy that HL-n could selectively
Ingunn Tho et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 40(1), 25-32 (2010-02-23)
The objective of the study was to characterise the aqueous dispersions of ritonavir melt extrudates. More specifically to look into the particular system formed when melt extrudate of a poorly soluble drug dissolved in a hydrophilic polymer matrix containing a
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service