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09569

Supelco

Span® 80

greener alternative

suitable for GC

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Synonym(s):
Sorbitan monooleate, Span® 80
Empirical Formula (Hill Notation):
C24H44O6
CAS Number:
Molecular Weight:
428.60
Beilstein/REAXYS Number:
8172514
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

description

non-ionic

Quality Level

mol wt

428.60 g/mol

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

technique(s)

LPLC: suitable
gas chromatography (GC): suitable
protein quantification: suitable

refractive index

n20/D 1.48 (lit.)

HLB value

4.6±0.1

density

0.99 g/mL at 20 °C
0.986 g/mL at 25 °C (lit.)

greener alternative category

SMILES string

[H][C@@](O)(COC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

InChI key

NWGKJDSIEKMTRX-AAZCQSIUSA-N

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1 of 4

This Item
85548S6760388920
vibrant-m

09569

Span® 80

vibrant-m

85548

Span® 80

vibrant-m

S6760

Span® 80

vibrant-m

388920

Sorbitan monopalmitate

mol wt

428.60 g/mol

mol wt

428.60 g/mol

mol wt

428.62 g/mol

mol wt

-

technique(s)

LPLC: suitable, gas chromatography (GC): suitable, protein quantification: suitable

technique(s)

-

technique(s)

-

technique(s)

-

density

0.99 g/mL at 20 °C, 0.986 g/mL at 25 °C (lit.)

density

0.99 g/mL at 20 °C, 0.986 g/mL at 25 °C (lit.)

density

-

density

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative product characteristics

-

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is biodegradable surfactant, thus aligns with "Use of Renewable Feedstocks" and "Design for Degradation" principles of Green Chemistry, and belongs to "12 principles aligned" category of our greener alternatives.

Application

A non-ionic surfactant that can be used to form oil-in-water emulsions and in combination with low HLB surfactants can form water-in-oil emulsions. EPA approved oil spill dispersant.

Legal Information

Span is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Faiyaz Shakeel et al.
Drug development and industrial pharmacy, 40(9), 1240-1245 (2013-07-11)
Abstract For the development of an effective self-nanoemulsifying drug delivery system (SNEDDS) of poorly soluble drugs, the knowledge of the solubility in its oil phase and SNEDDS are one of the most important factors to avoid possibility of drug to
Geneviève LeBel et al.
Applied and environmental microbiology, 80(17), 5484-5492 (2014-06-29)
Streptococcus suis serotype 2 is known to cause severe infections (meningitis, endocarditis, and septicemia) in pigs and is considered an emerging zoonotic agent. Antibiotics have long been used in the swine industry for disease treatment/prevention and growth promoters. This pattern
Keita Hayashi et al.
International journal of biological sciences, 9(2), 142-148 (2013-02-16)
Span 80 (sorbitan monooleate) vesicles behaved differently from conventional phospholipid vesicles (liposomes) because the former had a more fluid interface. After doxorubicin hydrochloride (DOX) was encapsulated into the Span 80 vesicle (loading efficiency: 63 %), DOX-loaded Span 80 vesicles (DVs)
Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 106, 258-264 (2013-02-26)
We have focused on the interaction between the Span 80 vesicle and phospholipid vesicle (liposome). The Span 80 vesicle was mixed with a phospholipid vesicle (liposome), used as a simplified model of plasma membrane. From calcein leakage experiments, it was
Jingchun Zhang et al.
Langmuir : the ACS journal of surfaces and colloids, 28(17), 6769-6775 (2012-04-06)
The effects of salt on emulsions containing sorbitan oleate (Span 80) and Laponite particles were investigated. Surprisingly, a novel double phase inversion was induced by simply changing the salt concentration. At fixed concentration of Laponite particles in the aqueous phase

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