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S7900

Sigma-Aldrich

Saponin from quillaja bark

Sapogenin content ≥10 %

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CAS Number:
EC Number:
MDL number:
NACRES:
NA.32

description

non-ionic

composition

Sapogenin content, ≥10%

technique(s)

HPLC: suitable
protein quantification: suitable

sulfated ash

<20%

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This Item
S45218451047036
vibrant-m

S7900

Saponin from quillaja bark

vibrant-m

S4521

Saponin Quillaja sp.

vibrant-m

84510

Saponin

vibrant-m

47036

Saponin

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

200

description

non-ionic

description

non-ionic

description

-

description

-

composition

Sapogenin content, ≥10%

composition

Sapogenin content, 20-35%

composition

Sapogenin, 8-25%

composition

Sapogenin, 8-25%

sulfated ash

<20%

sulfated ash

≤10%

sulfated ash

-

sulfated ash

-

General description

Saponins are natural steroidal glycoside (terpenes).

Application

Saponin from Quillaja bark has been used:
  • to stain CD4+ and CD8+ T-cells
  • to lyse trophozoite-infected red blood cells
  • in immunohistochemical staining

Biochem/physiol Actions

Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Hence it is used as vaccine adjuvants. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects.
Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.
Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.

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Warning

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Joo Young Park et al.
Journal of hazardous materials, 163(2-3), 761-767 (2008-08-12)
The applicability of microbubble suspension made of saponin as a biodegradation-enhancing carrier where oxygen and pollutant-degraders are limited was studied. The saponin-microbubble suspension was used to deliver phenanthrene-degrading bacteria, inorganic nutrients, and oxygen. Bench-scale study was carried out to determine
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