901568

Bromo-PEG₃-acid

• 実験式（ヒル表記法）: C₉H₁₇BrO₅
• CAS番号: 782475-35-8
• 分子量: 285.13
• MDL番号: MFCD22574820
• UNSPSCコード: 12352101
• NACRES: NA.22

特性

• 形状: liquid
• 反応適合性: reagent type: linker
• 官能基: bromo; carboxylic acid
• 保管温度: −20°C
• SMILES記法: BrCCOCCOCCOCCC(O)=O

詳細

アプリケーション

Bromo-PEG₃-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG₃-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.

法的情報

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3