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アッセイ
≥95%
フォーム
solid
反応適合性
reaction type: click chemistry
利用可能性
available only in USA
保管温度
2-8°C
SMILES記法
[n]1(nnc(c1)CN(Cc3nn[n](c3)C(C)(C)C)Cc2nn[n](c2)CC(=O)O)C(C)(C)C
InChI
1S/C19H30N10O2/c1-18(2,3)28-11-15(21-24-28)8-26(7-14-10-27(23-20-14)13-17(30)31)9-16-12-29(25-22-16)19(4,5)6/h10-12H,7-9,13H2,1-6H3,(H,30,31)
InChI Key
MGQYHUDOWOGSQI-UHFFFAOYSA-N
アプリケーション
BTTAA is a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTAA are advancements from water-insoluble TBTA and are desirable for bio conjugation in diverse chemical biology experiments.
その他情報
Biocompatible click chemistry enabled compartment-specific pH measurement inside E. coli
Fast, cell-compatible click chemistry with copper-chelating azides for biomolecular labeling
Metabolic labeling of fucosylated glycoproteins in Bacteroidales species
Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study
Fast, cell-compatible click chemistry with copper-chelating azides for biomolecular labeling
Metabolic labeling of fucosylated glycoproteins in Bacteroidales species
Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Self-react. C
保管分類コード
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
906328-BULK:
906328-100MG:
906328-500MG:
906328-VAR:
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Fast, cell-compatible click chemistry with copper-chelating azides for biomolecular labeling.
Chayasith Uttamapinant et al.
Angewandte Chemie (International ed. in English), 51(24), 5852-5856 (2012-05-05)
Samra Obeid et al.
Chemical communications (Cambridge, England), 48(67), 8320-8322 (2012-07-07)
Modified nucleotides play a paramount role in many cutting-edge biomolecular techniques. The present structural study highlights the plasticity and flexibility of the active site of a DNA polymerase while incorporating non-polar "Click-able" nucleotide analogs and emphasizes new insights into rational
Yongxian Xu et al.
Angewandte Chemie (International ed. in English), 57(15), 3949-3953 (2018-02-14)
Membrane voltage is an important biophysical signal that underlies intercellular electrical communications. A fluorescent voltage indicator is presented that enables the investigation of electrical signaling at high spatial resolution. The method is built upon the site-specific modification of microbial rhodopsin
Maiyun Yang et al.
Angewandte Chemie (International ed. in English), 51(31), 7674-7679 (2012-07-06)
Live-cell pH measurements: An environment-sensitive fluorophore (green) was site-specifically introduced on HdeA, an acid-resistant chaperone showing pH-mediated conformational changes under low pH conditions. A survey of the attachment sites led to the discovery of one position on HdeA at which
Yong Liang et al.
Analytical chemistry, 86(8), 3688-3692 (2014-03-25)
P450 3A4 (CYP3A4) is one of the most important isoforms in the human cytochrome P450 superfamily. It was used as an example in this proof-of-concept study in order to demonstrate an activity-based labeling and then click chemistry (CC) mediated element-tagging
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