E-901

Estazolam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₆H₁₁ClN₄
• CAS番号: 29975-16-4
• 分子量: 294.74
• EC Number: 200-659-6
• MDL番号: MFCD00867537
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• フォーム: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• 濃度: 1.0 mg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: clinical testing
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: Clc1ccc-2c(c1)C(=NCc3nncn-23)c4ccccc4
• InChI: 1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2
• InChI Key: CDCHDCWJMGXXRH-UHFFFAOYSA-N
• 遺伝子情報: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

詳細

詳細

A Certified Snap-N-Spike^® Solution appropriate for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research. Estazolam is a benzodiazepine prescribed for the short-term treatment of insomnia. Sold under trade names such as ProSom or Eurodin, estazolam is often abused recreationally to achieve a high or when long-term use is continued against physician advice.

アプリケーション

• Estazolam in environmental trace analysis: A study employing ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) detailed the detection of Estazolam among other psychotropic medications in environmental samples, underscoring the method′s precision and application in monitoring environmental contamination by pharmaceutical residues (Wang et al., 2024).


• Estazolam and insomnia post-coronavirus disease: Research analyzed insomnia prevalence among COVID-19 survivors, identifying Estazolam as part of the therapeutic regimen. This study highlights the ongoing relevance of Estazolam in addressing sleep disorders associated with long-term recovery from significant health events (Lu et al., 2024).


• Comparative analysis of Estazolam for post-stroke insomnia: A network meta-analysis compared various treatments for post-stroke insomnia, including Estazolam, providing insights into its effectiveness relative to other therapeutic options. This study contributes to understanding optimal treatment strategies for insomnia in post-stroke patients (Song et al., 2023).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P260 - P280 - P301 + P310 - P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup