1.37096

D-マンニトール

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

• 別名: マンニット
• 実験式（ヒル表記法）: C₆H₁₄O₆
• CAS番号: 69-65-8
• 分子量: 182.17
• Beilstein: 1721898
• MDL番号: MFCD00064287
• UNSPSCコード: 12352201
• EC Index Number: 200-711-8

特性

• 認証: BP; ChP; JP; Ph. Eur.; USP
• 品質水準: 500
• 製品種目: EMPROVE^® EXPERT
• 形状: solid
• 自己発火温度: 410 °C
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• bp: 290-295 °C/4 hPa
• mp: 167-170 °C (lit.)
• 溶解性: 213 g/L
• アプリケーション: liquid formulation; ophthalmics; parenterals; pharma/biopharma processes; pharmaceutical; semi-solid formulation; solid formulation
• 保管温度: 2-25°C
• SMILES記法: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI Key: FBPFZTCFMRRESA-KVTDHHQDSA-N

詳細

詳細

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Mannitol is a sugar alcohol which is used widely in biomolecule formulations as a stabilizer, bulking agent, and lyoprotecting agent, especially in lyophilization.
Due to its low microbial and endotoxin limits, D(-)-Mannitol Emprove^® Expert is especially suitable for high-risk applications.

生物化学的／生理学的作用

糖アルコールの甘味物質です。甘味阻害試験に用いられます。

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable