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Merck

38266

Millipore

フェリオキサミンE from Streptomyces antibioticus

suitable for microbiology, ≥95%

別名:

1,12,23-トリヒドロキシ-1,6,12,17,23,28-ヘキサアザシクロトリトリアコンタン-2,5,13,16,24,27-ヘキソン鉄(III)錯体

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About This Item

実験式(ヒル表記法):
C27H45FeN6O9
CAS番号:
分子量:
653.53
MDL番号:
UNSPSCコード:
41171614
PubChem Substance ID:
NACRES:
NA.85

無菌性

non-sterile

品質水準

アッセイ

≥95% (HPLC)
≥95%

フォーム

powder

損失

≤6% loss on drying

アプリケーション

environmental
food and beverages

microbiology

保管温度

2-8°C

適合性

Salmonella spp.

SMILES記法

[Fe+3].[O-]N1CCCCCNC(=O)CCC(=O)N([O-])CCCCCNC(=O)CCC(=O)N([O-])CCCCCNC(=O)CCC1=O

InChI

1S/C27H45N6O9.Fe/c34-22-10-14-26(38)32(41)20-8-3-6-18-30-24(36)12-15-27(39)33(42)21-9-2-5-17-29-23(35)11-13-25(37)31(40)19-7-1-4-16-28-22;/h1-21H2,(H,28,34)(H,29,35)(H,30,36);/q-3;+3

InChI Key

MZFKJKOHYACYNT-UHFFFAOYSA-N

詳細

Scientifically proven supplement for culture media improves detection of Salmonella, Enterobacter sakazakii and Yersinia enterocolitica .

Ferrioxamine E from Streptomyces antibioticum is a siderophore which facilitates the supply of iron (III), an essential trace element, to bacteria involved in food poisoning, including Salmonella, Enterobacter saka-zakii and Yersinia enterocolitica. It promotes rapid growth by reducing the lag phase in culture media and reactivates dormant bacteria. Use of ferrioxamine E can permit rapid detection of low bacterial cell counts, even from dry products like spices and tea after long storage periods. It is an essential component of quality control efforts in the food industry.

Ferrioxamine E is often used in Buffered Peptone Water, the medium recommended by the ISO-Norms for Enterobacteriacea. Ferrioxamine E also improves the motility of Salmonella, which helps to improve the identification by semisolid selective motility media like SIM, MRSV, DIASSALM or SMS. Ferrioxamine E does not improve growth of Escherichia coli, Shigella, Proteus, Providencia and Morganella species; a feature that makes it a semi-selective compound. The recommended concentration of Ferrioxamine E to promote bacterial growth is between 5 and 200 ng/mL
The ferrioxamines are basically metabolic products produced by the actinomycetes, and are characterised as ferrioxamines A, B, C, D 1, D2, E, F and G. Generally all ferrioxamines are trihydroxamates and the deferrioxamines are either linear or cyclic (D2 and E).

アプリケーション

濃縮前のブロスや濃縮済みブロスにフェリオキサミンEを加えると、人為的もしくは自然に汚染された食物からのサルモネラ菌の回収率が大幅に改善されます。

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

38266-BULK-F:
38266-9MG-F:4548174013458
38266-3MG-F:4548174013441
38266-VAR-F:


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I Berner et al.
Biology of metals, 1(1), 51-56 (1988-01-01)
Several strains of the enterobacterial group Erwinia herbicola (Enterobacter agglomerans) were screened for siderophore production. After 3 days of growth in a low-iron medium, all strains studied produced hydroxamate siderophores. The retention values of the main siderophore during thin-layer chromatography
Bradley L Bearson et al.
Microbial pathogenesis, 48(6), 214-219 (2010-03-17)
Salmonella enterica serovar Typhimurium (S. Typhimurium) responds to the catecholamine, norepinephrine by increasing bacterial growth and enhancing motility. In this study, iron with or without the siderophore, ferrioxamine E also enhanced bacterial motility. Iron-enhanced motility was growth-rate dependent, while norepinephrine-enhanced
R Reissbrodt et al.
Applied and environmental microbiology, 66(9), 4128-4130 (2000-08-31)
Storage of Salmonella enterica serovar Typhimurium strains in soil and water microcosms resulted in loss of culturability on standard plating media. Prior incubation in buffered peptone water supplemented with ferrioxamine E markedly extended the time that bacteria were recoverable by
Sanna Taskila et al.
Journal of food science, 76(3), M157-M162 (2011-05-04)
Rapid detection of Salmonella in foods is often limited by the high demand for the sensitivity of detection, poor physiological conditions of the target cells, and high concentration of background flora. In this study, the conditions of nonselective enrichment cultivation were modified
Milos Petrik et al.
European journal of nuclear medicine and molecular imaging, 39(7), 1175-1183 (2012-04-25)
Invasive pulmonary aspergillosis is mainly caused by Aspergillus fumigatus, and is one of the major causes of morbidity and mortality in immunocompromised patients. The mortality associated with invasive pulmonary aspergillosis remains high, mainly due to the difficulties and limitations in

資料

Microbiological assessment of bacteria found in spices, a potent source for food spoilage and pathogens.

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