PHR1307

カプトプリル

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: N-[(S)-3-メルカプト-2-メチルプロピオニル]-L-プロリン
• 実験式（ヒル表記法）: C₉H₁₅NO₃S
• CAS番号: 62571-86-2
• 分子量: 217.29
• Beilstein: 477887
• EC Number: 263-607-1
• MDL番号: MFCD00168073
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823294
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 538; traceable to Ph. Eur. C0430000; traceable to USP 1091200
• APIファミリー: captopril
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 104-108 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
• InChI: 1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
• InChI Key: FAKRSMQSSFJEIM-RQJHMYQMSA-N
• 遺伝子情報: human ... ACE(1636)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Captopril acts by inhibiting the angiotensin-converting enzyme and is known as an antihypertensive agent. It finds wide use in the treatment of congestive heart failure.

アプリケーション

Captopril may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various analytical techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

アンジオテンシン変換酵素阻害剤です。アンジオテンシンⅡの形成を阻害します。血管形成を促進し、微小血管密度を増加させる生理活性ペプチドです。

アナリシスノート

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA0067 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H341,H360F
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Muta. 2 - Repr. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable