PHR1636

アゼラスチン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 4-[(4-クロロフェニル)メチル]-2-(1-メチルアゼパン-4-イル)フタラジン-1-オン 塩酸塩, アステリン, オプティバール
• 実験式（ヒル表記法）: C₂₂H₂₄ClN₃O · HCl
• CAS番号: 79307-93-0
• 分子量: 418.36
• MDL番号: MFCD00242783
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823526
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. Y0000326; traceable to USP 1046158
• APIファミリー: azelastine
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: Cl.CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O
• InChI: 1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
• InChI Key: YEJAJYAHJQIWNU-UHFFFAOYSA-N
• 遺伝子情報: human ... HRH1(3269)

詳細

詳細

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Azelastine Hydrochloride is a long-acting antiallergic and antiasthmatic drug.

アプリケーション

Azelastine Hydrochloride may be used as a pharmaceutical secondary reference standard for the determination of azelastine in plasma samples by manual-injection liquid chromatographic method using fluorescence detection.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

H1ヒスタミン受容体のアンタゴニストであり、NF-kBアクチベーターです。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA5303 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable