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9-Fluorenylmethoxycarbonyl chloride (Fmoc-Cl) is a reagent for pre-column derivatization of amino acids and biogenic amines for HPLC amino acid analysis and for preparing N-Fmoc amino acids for solid-phase peptide synthesis.
HPLCアミノ酸分析や、固相ペプチド合成のためのN-Fmocアミノ酸調製に用いられるアミノ酸誘導体化試薬です。
その他情報
アミノ酸のプレカラム蛍光誘導体化に用いられる試薬です 。
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シグナルワード
Danger
危険有害性情報
危険有害性の分類
Eye Dam. 1 - Skin Corr. 1B
補足的ハザード
保管分類コード
8A - Combustible corrosive hazardous materials
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
23184-BULK:
23184-VAR:
23184-1G:
23184-5G:
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E J Miller et al.
Analytical biochemistry, 190(1), 92-97 (1990-10-01)
A recently described procedure for amino acid analyses has been modified and adapted for use in quantitating the unique mixture of products commonly found in hydrolysates of the collagens. The method involves precolumn derivatization of hydrolysates with 9-fluorenylmethyl chloroformate (FMOC-CL)
Valentin Lozanov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 860(1), 92-97 (2007-11-07)
A liquid chromatography method for simultaneous analysis of amino acids, polyamines, catecholeamines and metanephrines in human body fluids after derivatization with 9-fluorenylmethyloxycarbonyl chloride was developed. The chromatographic behavior of analytes at different pH of mobile phase was studied. Successful baseline
Ibolya Molnár-Perl
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(17-18), 1241-1269 (2011-03-05)
An overview is presented on the advancement of the two most frequently used derivatization protocols applying the o-phthalaldehyde (OPA)-thiol and the fluorenylmethyloxycarbonyl (FMOC) chloride reagents, prior to the high performance liquid chromatographic analysis of amino acids. This review pays special
P Fürst et al.
Journal of chromatography, 499, 557-569 (1990-01-19)
Reversed-phase high-performance liquid chromatography (RP-HPLC) is a powerful method for assaying physiological amino acid concentrations in biological fluids. Four pre-column derivatization methods, with o-phthaldialdehyde (OPA), 9-fluorenylmethyl chloroformate (FMOC-Cl), phenyl isothiocyanate (PITC) and 1-dimethylaminonaphthalene-5-sulphonyl chloride (dansyl-Cl), were assessed with respect to
A Jámbor et al.
Journal of chromatography. A, 1216(34), 6218-6223 (2009-07-28)
This paper, as a novelty to this field, presents the deproteinization and derivatization of plasma's free amino acids (PFAAs), simultaneously, in a single step, with the acetonitrile (ACN) containing 9-fluorenylmethyloxycarbonyl chloride (FMOC) reagent. Deproteinization and derivatization, were studied with 22
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