68957

トリス（2-カルボキシエチル）ホスフィン 塩酸塩

BioUltra, suitable for electrophoresis, SDS-PAGE tested

• 別名: TCEP
• 実験式（ヒル表記法）: C₉H₁₅O₆P · HCl
• CAS番号: 51805-45-9
• 分子量: 286.65
• Beilstein: 3724376
• MDL番号: MFCD00145469
• UNSPSCコード: 12352128
• PubChem Substance ID: 329761275
• NACRES: NA.32

特性

• 製品種目: BioUltra
• 品質水準: 100
• アッセイ: 97.5-102.5%
• 形状: powder
• テクニック: electrophoresis: suitable
• 溶解性: H₂O: soluble
• 適合性: SDS-PAGE tested
• SMILES記法: Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
• InChI: 1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
• InChI Key: PBVAJRFEEOIAGW-UHFFFAOYSA-N

詳細

詳細

Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.

アプリケーション

TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.

水溶性の試薬であり、ジスルフィドの選択的還元に使用されます。DTTよりも高い安定性を示し、質量分析での使用に有用です。

特徴および利点

The product has the following benefits:

• TCEP.HCL lowers reactive oxygen species levels.
• It increases glutathione levels and mitochondrial content.
• It has anti-cancer effects.

アナリシスノート

agarose gel electrophorese corresponds to requirements

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Danger
• 危険有害性情報: H314
• 注意書き: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• 危険有害性の分類: Eye Dam. 1 - Skin Corr. 1B
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1