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品質水準
オーガナイザー
Boehringer Ingelheim
SMILES記法
Br[H].CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2
InChI
1S/C17H21NO4.BrH/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13;/h2-5,7-9,11,17-22H,6,10H2,1H3;1H
InChI Key
SGZRQMALQBXAIQ-UHFFFAOYSA-N
遺伝子情報
human ... ADRB2(154)
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詳細
Fenoterol hydrobromide is a sympathomimetic drug. It is used to treat asthma, bronchitis and emphysema. Fenoterol administration might be linked to liver damage. It has anti-inflammatory effects on eosinophil function.
アプリケーション
Fenoterol hydrobromide has been used in chromatography-tandem mass spectrometry (LC&-MS-MS) for specific and sensitive detection of β-agonists (BAG).
生物化学的／生理学的作用
β2-アドレナリンレセプタ-アゴニストであり、気管支拡張薬です。
特徴および利点
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral
保管分類コード
11 - Combustible Solids
WGK
WGK 3
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
F1016-1G:
F1016-BULK:
F1016-250MG:
F1016-VAR:
F1016-100MG:
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Julia J Rucklidge et al.
Human psychopharmacology, 27(5), 440-454 (2012-07-12)
To compare two micronutrient (vitamins and minerals) formulas (Berocca™ and CNE™) and assess their impact on emotions and stress related to the 6.3 earthquake on February 22(nd) 2011 in Christchurch, New Zealand. 91 adults experiencing heightened anxiety or stress 2-3 months
Lawrence Toll et al.
Molecular pharmacology, 81(6), 846-854 (2012-03-22)
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a molecule with a G protein-coupled
Joanne Chung Yan Yeung et al.
Analytica chimica acta, 742, 37-44 (2012-08-14)
In vivo solid-phase microextraction (SPME) can be used to sample the circulating blood of animals without the need to withdraw a representative blood sample. In this study, in vivo SPME in combination with liquid-chromatography tandem mass spectrometry (LC-MS/MS) was used
T Katsunuma et al.
American journal of respiratory cell and molecular biology, 21(3), 409-417 (1999-08-26)
Neurokinin A (NKA) induces bronchoconstriction mediated by tachykinin NK(2) receptors in animals and humans, and may be increased in asthma. Because beta(2)-adrenoceptor agonists are the most widely used bronchodilators in asthma, we investigated the effects of the beta(2)-adrenoceptor agonist fenoterol
Krzysztof Jozwiak et al.
Chirality, 23 Suppl 1, E1-E6 (2011-05-28)
The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies
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