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詳細
Myoglobin is a heme-related, low-molecular-weight protein. It is mainly found in cardiac and skeletal muscle.
アプリケーション
Myoglobin from human heart has been used as a negative control in monitoring isoAsp formation during storage. It has also been used as an antigen in the study to identify self-antigens recognized by serum autoantibodies from unimmunized mice strains.
Myoglobin from human heart was used to study the interactions of a platinum (II) 9-aminoacridine complex with proteins and oligonucleotides by ESI-TOF MS. It was also used in the evaluation of plasma myoglobin using the Stratus CS fluorometer.
生物化学的／生理学的作用
Myoglobin may help to increase diffusion and also stores O2 in oxidative muscle. It can momentarily act as an oxygen reservoir to supply oxygen when there is inadequate blood oxygen delivery at the time of intense muscular activity.
物理的形状
20 mM Tris-HCl, 1 mM EDTA, 50%グリセロ-ルに溶解された(pH 8.5)、2 mgタンパク質/mL(Lowry法で測定)溶液
保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
M6036-VAR:
M6036-250UG-PW:
M6036-250UG:
M6036-BULK:
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試験成績書（COA）
Lot/Batch Number
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Iron metabolism and its disorders
Clinical biochemistry of domestic animals, 259-285 (2008)
A High-Throughput Bioluminescent Assay to Monitor the Deamidation of Asparagine and Isomerization of Aspartate Residues in Therapeutic Proteins and Antibodies
Hsiao K, et al.
Journal of Pharmaceutical Sciences, 106(6), 1528-1537 (2017)
Signe Helbo et al.
PloS one, 9(5), e97012-e97012 (2014-06-01)
The discovery that cysteine (Cys) S-nitrosation of trout myoglobin (Mb) increases heme O2 affinity has revealed a novel allosteric effect that may promote hypoxia-induced nitric oxide (NO) delivery in the trout heart and improve myocardial efficiency. To better understand this
Diagnosis of Acute Myocardial Infarction
Cardiac Intensive Care (Second Edition) (2010)
Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice
Quintana F J and Cohen I R
Journal of Autoimmunity, 17(3), 191-197 (2001)
Chromatograms
application for HPLCライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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