S9132

スピラマイシン

• 別名: ホルマシジン
• CAS番号: 8025-81-8
• EC Number: 232-429-6
• MDL番号: MFCD01314545
• UNSPSCコード: 51283208
• PubChem Substance ID: 24899826
• NACRES: NA.85

特性

• フォーム: powder
• 品質水準: 200
• 光学活性: [α]/D -85 to -80° in water (Specific rotation (dry basis))
• 有効性: ≥4100 I.U. per mg (dry basis)
• 保管条件: (Keep container tightly closed in a dry and well-ventilated place.)
• 色: white to light yellow
• 溶解性: methanol: soluble
• 微量陽イオン: heavy metals: ≤20 ppm
• 抗生物質活性スペクトル: Gram-positive bacteria
• 作用機序: protein synthesis | interferes
• 保管温度: 2-8°C
• SMILES記法: CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C
• InChI: 1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
• InChI Key: ACTOXUHEUCPTEW-JMRHEKERSA-N

詳細

詳細

Chemical structure: macrolide

アプリケーション

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

生物化学的／生理学的作用

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

品質

スピラマイシンI、IIおよびIIIの混合物。

その他情報

Keep container tightly closed in a dry and well-ventilated place.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)