42597
3′-Deoxythymidine 5′-triphosphate sodium salt solution
BioChemika, puriss. p.a., suitable for MALDI-MS, ≥98.0% (HPLC)
동의어(들):
2′,3′-Dideoxythymidine 5′-triphosphate, ddTTP
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C10H16N2NaO13P3
CAS Number:
Molecular Weight:
488.15
MDL number:
UNSPSC 코드:
41116105
PubChem Substance ID:
추천 제품
제품 라인
BioChemika
grade
puriss. p.a.
분석
≥98.0% (HPLC)
농도
10.0-11.0 mmol/L (UV)
기술
MALDI-MS: suitable
불순물
≤1.5% ddNDP (HPLC)
적합성
corresponds for UV test
저장 온도
−20°C
SMILES string
[Na+].CC1=CN([C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
InChI
1S/C10H17N2O13P3.Na/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17;/h4,7-8H,2-3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17);/q;+1/p-1/t7-,8+;/m0./s1
InChI key
QJSZKDPCBDXBCK-KZYPOYLOSA-M
일반 설명
3′-Deoxythymidine 5′-triphosphate sodium (ddTTP) is a sugar-modified dTTP analogue which is selective inhibitor of HIV-associated reverse transcriptase (HIV-RT). It is also seen to inhibit the activity of DNA polymerase α.
포장
packaging : 1 μmol (approx. 91-100 μL)
관련 제품
제품 번호
설명
가격
교체됨
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Sylvia Steininger et al.
Nucleic acids research, 38(6), 1853-1865 (2009-12-31)
The Mre11/Rad50/Xrs2 (MRX) complex in Saccharomyces cerevisiae has well-characterized functions in DNA double-strand break processing, checkpoint activation, telomere length maintenance and meiosis. In this study, we demonstrate an involvement of the complex in the base excision repair (BER) pathway. We
Elena N Ilina et al.
Frontiers in microbiology, 4, 186-186 (2013-07-13)
Spectinomycin remains a useful reserve option for therapy of gonorrhea. The emergence of multidrug-resistant Neisseria gonorrhoeae strains with decreased susceptibility to cefixime and to ceftriaxone makes it the only medicine still effective for treatment of gonorrhea infection in analogous cases.
Juan Gambini et al.
Antioxidants (Basel, Switzerland), 10(2) (2021-03-07)
The beneficial effects of moderate red wine consumption on cardiovascular health are well known. The composition of red wine includes several compounds, such as the phytoestrogen resveratrol, that exert these beneficial effects, although not all the mechanisms by which they
E Matthes et al.
Biochemical and biophysical research communications, 148(1), 78-85 (1987-10-14)
The sugar-modified dTTP analogues 2',3'-didehydro-2',3'-dideoxy-thymidine 5'-triphosphate (ddeTTP), 2',3'-dideoxythymidine 5'-triphosphate (ddTTP), 3'-fluorothymidine 5'-triphosphate (FdTTP), and 3'-azidothymidine 5'-triphosphate (N3dTTP) are demonstrated to be very effective and selective inhibitors of the HIV-associated reverse transcriptase (HIV-RT). This conclusion is based on a comparison of
Konstantin Akopiants et al.
Nucleic acids research, 42(5), 3125-3137 (2013-12-29)
To track the processing of damaged DNA double-strand break (DSB) ends in vivo, a method was devised for quantitative measurement of 3'-phosphoglycolate (PG) termini on DSBs induced by the non-protein chromophore of neocarzinostatin (NCS-C) in the human Alu repeat. Following
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