모든 사진(1)
About This Item
실험식(Hill 표기법):
C13H12N2O5S
CAS Number:
Molecular Weight:
308.31
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
생물학적 소스
synthetic (organic)
Quality Level
분석
≥98% (TLC)
양식
powder
solubility
ethanol: 50 mg/mL
저장 온도
2-8°C
SMILES string
CS(NC1=C(OC2=CC=CC=C2)C=C([N+]([O-])=O)C=C1)(=O)=O
InChI
1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
InChI key
HYWYRSMBCFDLJT-UHFFFAOYSA-N
유전자 정보
human ... ALB(213) , PTGS1(5742) , PTGS2(5743)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID) belongs to the sulfonanilide class.
애플리케이션
Nimesulide has been used as a component in the reaction mixture to determine the activity of cyclooxygenase (COX) in spleen of chickens.
생화학적/생리학적 작용
Highly selective cyclooxygenase-2 inhibitor.
Nimesulide can be used as a substitute to other nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain and inflammation of osteoarthritis for a short period. It can perform anti-inflammatory, analgesic and antipyretic activities.
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
이미 열람한 고객
Effects of dietary fish oil on NF
Yang X, et al.
The Journal of animal ecology, 20(3), 206-223 (2011)
Nimesulide
Davis R and Brogden R N
Drugs, 48(3), 431-454 (1994)
Yuan Yuan et al.
International journal of pharmaceutics, 430(1-2), 114-119 (2012-04-17)
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Brijesh Kumar Singh et al.
PloS one, 7(4), e34200-e34200 (2012-04-18)
Nimesulide, an anti-inflammatory and analgesic drug, is reported to cause severe hepatotoxicity. In this study, molecular mechanisms involved in deranged oxidant-antioxidant homeostasis and mitochondrial dysfunction during nimesulide-induced hepatotoxicity and its attenuation by plant derived terpenes, camphene and geraniol has been
Renata P Raffin et al.
Journal of biomedical nanotechnology, 8(2), 309-315 (2012-04-21)
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