MilliporeSigma

1.03669

SAFC

Glycine

granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Synonym(s):
Gly, Aminoacetic acid, Aminoethanoic acid, Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
MDL number:
EC Index Number:
200-272-2

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

vapor pressure

0.0000171 Pa ( 25 °C)

description

granulated EMPROVE® EXPERT Ph.Eur.,BP,JP,USP

product line

EMPROVE® EXPERT

Assay

99.0-101.0% (calculated on dried substance, perchloric acid titration)

form

granular

technique(s)

inhibition assay: suitable

pH

5.9-6.4 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

density

1.161 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

2-30°C

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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This Item
4102254810-OPG5417
Glycine granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

SAFC

1.03669

Glycine

Glycine ACS reagent, ≥98.5%

Sigma-Aldrich

410225

Glycine

OmniPur® Glycine

Millipore

4810-OP

OmniPur® Glycine

Glycine

SAFC

G5417

Glycine

assay

99.0-101.0% (calculated on dried substance, perchloric acid titration)

assay

≥98.5%

assay

-

assay

≥98.5%

form

granular

form

powder, crystals or granules

form

crystalline powder

form

crystalline powder

technique(s)

inhibition assay: suitable

technique(s)

-

technique(s)

-

technique(s)

cell culture | mammalian: suitable

pH

5.9-6.4 (20 °C, 50 g/L in H2O)

pH

-

pH

-

pH

5.9-6.4

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing processes and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, granulated glycine is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Glycine in general is widely used in the biopharma industry as a stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine granulated Emprove® Expert is especially suitable for high-risk applications.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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1295800

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Glycine

Glycine ACS reagent, ≥98.5%

Sigma-Aldrich

410225

Glycine

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SAFC

C5735

L-Cystine

Glycine BioUltra, for molecular biology, ≥99.0% (NT)

Sigma-Aldrich

50046

Glycine

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