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50058

Sigma-Aldrich

Glycine

tested according to Ph. Eur.

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Synonym(s):
Glycinum, Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein/REAXYS Number:
635782
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

agency

USP/NF
tested according to Ph. Eur.

Quality Level

assay

100.0%

form

crystalline

color

white

pH

6.2

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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1 of 4

This Item
PHR1111G5417410225
Glycine tested according to Ph. Eur.

50058

Glycine

Glycine Pharmaceutical Secondary Standard; Certified Reference Material

PHR1111

Glycine

Glycine

G5417

Glycine

Glycine ACS reagent, ≥98.5%

410225

Glycine

assay

100.0%

assay

-

assay

≥98.5%

assay

≥98.5%

Quality Level

200

Quality Level

300

Quality Level

400

Quality Level

200

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

color

white

color

-

color

-

color

white

agency

USP/NF

agency

traceable to Ph. Eur. G0450000, traceable to USP 1295800

agency

-

agency

-

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Li-Chun Tu et al.
The EMBO journal, 32(24), 3220-3230 (2013-11-12)
Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major impediments
Suzanne L Grant et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 278-282 (2006-08-08)
A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in
Steven Tran et al.
Behavioural brain research, 276, 161-170 (2014-03-07)
The zebrafish is emerging as a popular animal model for alcohol (ethanol or EtOH) addiction due to its simplicity and practical advantages. Two phenomena associated with ethanol addiction are the development of tolerance and withdrawal. Using a multi-level approach in

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