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90190

Sigma-Aldrich

Transferrin from human blood plasma

≥95% (GE)

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Synonym(s):
Human transferrin, Siderophilin
CAS Number:
EC Number:
MDL number:
NACRES:
NA.61

biological source

human plasma

Quality Level

assay

≥95% (GE)

form

powder or crystals

mol wt

Mr ~79550

technique(s)

tissue culture: suitable

impurities

≤0.01% iron traces (AAS)

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow or pink

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... TF(7018)

Application

Transferrin is an important supplement in serum-free tissue culture media.

Biochem/physiol Actions

Transferrin is glycoprotein, approx. 80 kDa, with two binding sites for iron. It transports iron from its primary store in the liver to tissues that require iron, primarily bone marrow and spleen, but also brain. It binds Fe3+ extremely tightly (Kdiss 10-30 to 10-27), protecting against oxidant effects of free plasma iron.

Other Notes

Review: Iron transport and storage

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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