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- Removal of GenX by APTES functionalized diepoxyoctane cross-linked chitosan beads: Cross-linked and aminated chitosan beads were synthesized using 1,2:7,8-diepoxyoctane and 3-aminopropyl triethoxysilane. These beads were studied for their efficiency in removing GenX, a problematic environmental pollutant, demonstrating a potential application in water treatment technologies (M Vakili, F Gholami, HM Zwain, W Wang… - Journal of …, 2023 - Elsevier).
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Carc. 1B - Muta. 2
保管分類コード
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
引火点(°F)
208.4 °F - closed cup
引火点(℃)
98 °C - closed cup
個人用保護具 (PPE)
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
消防法
第4類:引火性液体
第三石油類
危険等級III
非水溶性液体
Jan Code
139564-VAR:
139564-50G:
139564-BULK:
139564-10G:
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Chemical research in toxicology, 9(6), 994-1000 (1996-09-01)
The carcinogenicity of epoxide compounds has been attributed to covalent binding to DNA. Whereas monoepoxides form only monoadducts, diepoxides can form both monoadducts and interstrand cross-links. The latter are believed to be the more significant cytotoxic lesions as diepoxides are
Biochemistry, 40(35), 10677-10685 (2001-08-29)
Diepoxyalkanes form interstrand cross-links in DNA oligomers preferentially at 5'-GNC sites. We have examined cross-linking by 1,2,3,4-diepoxybutane (DEB) and 1,2,7,8-diepoxyoctane (DEO) within a fragment of the 5S RNA gene of Xenopus borealis in both the free and nucleosomal states. Sites
Molecular and cellular biology, 5(1), 1-6 (1985-01-01)
The mutation e1662 is an allele of the Caenorhabditis elegans unc-54 gene induced with the difunctional alkylating agent 1,2,7,8-diepoxyoctane. unc-54 encodes the major myosin heavy chain isozyme of body wall muscle cells. Filter-transfer hybridization and DNA sequence analysis show that
The Biochemical journal, 251(3), 935-938 (1988-05-01)
A new method for the chemical labelling of nucleic acid with biotin to produce non-radioactive probes has been developed. NN'-Bis-(3-aminopropyl)butane-1,4-diamine (spermine) and long-chain diamino compounds (diaminohexane, diaminodecane and diaminododecane) were linked covalently to biotin and the resultant conjugates were attached
Mutation research, 441(1), 85-93 (1999-05-04)
The time-dependent dose-response relationships for the induction of DNA double-strand breaks (DSB) assessed by pulsed-field gel electrophoresis (PFGE) and for viability (evaluated by the MTT cytotoxicity test) were investigated in order to discriminate between genotoxic and cytotoxic mechanisms of DNA
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