764191

Alkyne-PEG5-N-hydroxysuccinimidyl ester

• 別名: Acetylene-PEG5-NHS ester, Alkyne-PEG5-NHS ester, Alkyne-PEG5-succinimidyl ester
• 実験式（ヒル表記法）: C₁₈H₂₇NO₉
• 分子量: 401.41
• MDL番号: MFCD22574798
• UNSPSCコード: 12352108
• PubChem Substance ID: 329767105
• NACRES: NA.22

特性

• 形状: liquid
• 品質水準: 100
• 反応適合性: reaction type: click chemistry; reagent type: cross-linking reagent
• 官能基: NHS ester; alkyne
• 保管温度: −20°C
• SMILES記法: C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
• InChI: 1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2
• InChI Key: ACZDUKRWTPZVRP-UHFFFAOYSA-N

詳細

アプリケーション

Heterobifunctional crosslinker enabling the connection of an azide containing compound or biomolecule to one with a primary amine. The succinimidyl ester group will react preferentially with primary amines to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification amine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable