900831

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

• 別名: Carboxyl diazirine alkyne, Probe building block
• 実験式（ヒル表記法）: C₈H₁₀N₂O₂
• CAS番号: 1450754-37-6
• 分子量: 166.18
• MDL番号: MFCD31433997
• UNSPSCコード: 12352106

特性

• 形状: liquid
• 品質水準: 100
• 反応適合性: reaction type: click chemistry
• 利用可能性: available only in USA
• 保管温度: −20°C
• SMILES記法: C#CCCC1(N=N1)CCC(O)=O

詳細

アプリケーション

Used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

その他情報

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein

Technology Spotlight: Trifuctional Probe Building Blocks

安全性情報

• ピクトグラム: GHS02
• シグナルワード: Danger
• 危険有害性情報: H242
• 注意書き: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危険有害性の分類: Self-react. C
• 保管分類コード: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable