900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 別名: Bromo sulfonyl fluoride alkyne, Probe building block
• 実験式（ヒル表記法）: C₁₂H₁₄BrFO₂SSi
• CAS番号: 2088829-12-1
• 分子量: 349.29
• MDL番号: MFCD30737997
• UNSPSCコード: 12352200
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: ≥95%
• フォーム: solid
• 反応適合性: reaction type: click chemistry
• 保管温度: −20°C
• SMILES記法: [Si](C)(C)(C)C#Cc1cc(cc(c1)CBr)[S](=O)(=O)F
• InChI: 1S/C12H14BrFO2SSi/c1-18(2,3)5-4-10-6-11(9-13)8-12(7-10)17(14,15)16/h6-8H,9H2,1-3H3
• InChI Key: QSYGHPYMWBAJRL-UHFFFAOYSA-N

詳細

アプリケーション

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

その他情報

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable