65943

N-メチル-ビス(トリフルオロアセトアミド)

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• 別名: MBTFA
• 化学式: CF₃CON(CH₃)COCF₃
• CAS番号: 685-27-8
• 分子量: 223.07
• Beilstein: 1878402
• EC Number: 211-680-5
• MDL番号: MFCD00000412
• UNSPSCコード: 12000000
• PubChem Substance ID: 329760134
• NACRES: NA.22

特性

• グレード: for GC derivatization
• 品質水準: 100
• アッセイ: ≥99.0% (GC)
• 品質: LiChropur^™
• 反応適合性: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Silylations
• テクニック: gas chromatography (GC): suitable
• 屈折率: n20/D 1.346 (lit.); n20/D 1.346
• bp: 121-122 °C (lit.)
• 密度: 1.547 g/mL at 25 °C
• SMILES記法: CN(C(=O)C(F)(F)F)C(=O)C(F)(F)F
• InChI: 1S/C5H3F6NO2/c1-12(2(13)4(6,7)8)3(14)5(9,10)11/h1H3
• InChI Key: AWGBWLXGUPTXHF-UHFFFAOYSA-N

詳細

詳細

N-Methyl-bis(trifluoroacetamide) is a common reagent used in the alkylation process, which targets highly polar, multi-functional compounds such as carbohydrates and amino acids.

アプリケーション

N-Methyl-bis(trifluoroacetamide) may be used as an on-column derivatization agent for the determination of amphetamine-type stimulants in biological samples, and ketamine, norketamine, dehydronorketamine in urine samples using gas chromatography coupled to mass spectrometry technique.
It is a derivatization agent in GC-MS technique used as an alternative to trifluoroacetyl anhydride (TFAA) for trifluoroacylating primary and secondary amines, and the hydroxyl group under mild non-acidic conditions.
Reagent for introducing trifluoroacetyl group. Suitable for the derivatization of alcohols, amines, amino acids, carbohydrates(mono-,di-,tri- and tetrasaccharides, carboxylic acids, hydroxyamines, 3-hydroxy-1-nitrosopyrrolidine, indolalkylamine, phenolalkylamines, pyridoxal (and other B₆ vitamers), and thiols.

トリフルオロアセチル基を導入する試薬

その他情報

Reagent for trifluoroacetyl, N-trimethylsilyl-N-tifluoroacetyl and trimethylsilyl.

Reagent for trifluoroacetylations under mild conditions

法的情報

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS05
• シグナルワード: Danger
• 危険有害性情報: H226,H314
• 注意書き: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Flam. Liq. 3 - Skin Corr. 1B
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 113.0 °F - closed cup
• 引火点(℃): 45 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter