BP578

Dexamethasone

British Pharmacopoeia (BP) Assay Standard

• 동의어(들): (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F
• 실험식(Hill 표기법): C₂₂H₂₉FO₅
• CAS Number: 50-02-2
• Molecular Weight: 392.46
• Beilstein: 2066651
• EC Number: 200-003-9
• MDL number: MFCD00064136
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: dexamethasone
• 형태: solid
• 유통기한: limited shelf life, expiry date on the label
• 제조업체/상표: BP
• mp: 262-264 °C (lit.)
• 응용 분야: pharmaceutical; pharmaceutical small molecule
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• InChI key: UREBDLICKHMUKA-CXSFZGCWSA-N
• 유전자 정보: human ... NR3C1(2908)

설명

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Dexamethasone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tobramycin and Dexamethasone Eye Drops, Suspension

Dexamethasone Sodium Phosphate Oral Solution

Hydrocortisone Sodium Succinate Injection

Prednisolone Tablets

Dexamethasone Eye Drops, Suspension

Dexamethasone Sodium Phosphate Eye Drops, Solution

Dexamethasone and Neomycin Ear Spray

Betamethasone Tablets

Dexamethasone Tablets

생화학적/생리학적 작용

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

기타 정보

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360FD
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable