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648311

Millipore

Tris Base

ULTROL® Grade, ≥99% dry basis (titration), useful in pH range 10.3-11.3

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Synonym(s):
Tris(hydroxymethyl)aminomethane, tris(Hydroxymethyl)aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein/REAXYS Number:
741883
MDL number:

Quality Level

assay

≥99% dry basis (titration)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

solubility

water: 1 M

cation traces

heavy metals: ≤5 ppm

shipped in

ambient

storage temp.

10-30°C

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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This Item
93350T6066RDD008
vibrant-m

648311

Tris Base

-
vibrant-m

93350

Trizma® base

-
vibrant-m

T6066

Trizma® base

Premium Grade
vibrant-m

RDD008

Trizma® base

-
Quality Level

100

Quality Level

200

Quality Level

400

Quality Level

100

form

crystalline solid

form

crystalline

form

crystalline powder

form

powder

solubility

water: 1 M

solubility

water: soluble (678 g/l at 20 °C)

solubility

water: soluble (666 mg/ml, yielding a clear colorless solution)

solubility

water: soluble (Water < 0.2%)

storage condition

OK to freeze

storage condition

-

storage condition

-

storage condition

-

storage temp.

10-30°C

storage temp.

-

storage temp.

-

storage temp.

-

General description

Absorbance (1.0 M, H2O, 260 nm): <0.05.
Useful in the pH range of 10.3-11.3. Has a pKa of 8.1 at 25°C.
Widely used as a biological buffer (absorbance: <0.05 at 260 nm, 1.0 M, H2O). A 1.0 M solution in H2O has a pH range of 10.3-11.3 and a pKa of 8.3 at 20°C.

Warning

Toxicity: Irritant (B)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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International journal of molecular sciences, 20(24) (2019-12-19)
Eyes absent (EYA) are non-thiol-based protein tyrosine phosphatases (PTPs) that also have transcriptional co-activator functions. Their PTP activity is involved in various pathologies. Recently, we demonstrated that Src tyrosine kinase phosphorylates human EYA3 by controlling its subcellular localization. We also

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