861650

(+)-Biotin 4-nitrophenyl ester

98%

• 別名: 4-Nitrophenyl (+)-biotinate, d-Biotin p-nitrophenyl ester, BNP
• 実験式（ヒル表記法）: C₁₆H₁₉N₃O₅S
• CAS番号: 33755-53-2
• 分子量: 365.40
• Beilstein: 5795805
• MDL番号: MFCD15141972
• UNSPSCコード: 12352108
• PubChem Substance ID: 24888552
• NACRES: NA.22

特性

• 品質水準: 200
• アッセイ: 98%
• 形状: powder
• 光学活性: [α]25/D +51°, c = 2 in DMF: AcOH (99:1)
• mp: 163-165 °C (lit.)
• 溶解性: methanol: 25 mg/mL, clear, colorless to greenish-yellow
• 官能基: ester; nitro; thioether
• SMILES記法: [O-][N+](=O)c1ccc(OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)cc1
• InChI: 1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
• InChI Key: YUDNXDTXQPYKCA-YDHLFZDLSA-N

詳細

アプリケーション

(+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[¹⁷O]H to form [¹⁷O₂]biotin, which can be used in solid-state ¹⁷O NMR spectroscopic experiments to analyze large protein-ligand complexes.

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包装

底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)