27029

コール酸ナトリウム 水和物

≥97.0% (dried material, NT)

• 別名: 3α,7α,12α-トリヒドロキシ-5β-コラン-24-酸 ナトリウム塩, コール酸 ナトリウム塩
• 実験式（ヒル表記法）: C₂₄H₃₉NaO₅ · xH₂O
• CAS番号: 206986-87-0
• 分子量: 430.55 (anhydrous basis)
• Beilstein: 3582354
• EC Number: 206-643-5
• MDL番号: MFCD00150749
• UNSPSCコード: 12161900
• PubChem Substance ID: 57648188
• NACRES: NA.25

特性

• 詳細: anionic
• 品質水準: 200
• アッセイ: ≥97.0% (dried material, NT)
• フォーム: powder
• 光学活性: [α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
• 分子量: micellar avg mol wt 900-1300
• 凝集数: 2-3
• 損失: ≤5% loss on drying
• CMC: 9-15 mM (20-25°C)
• 溶解性: H₂O: 0.1 M; H₂O: 100 mg/mL
• HLB: 18
• SMILES記法: O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
• InChI Key: MUVVIYFKOVLQHL-RCVKHMDESA-M

詳細

詳細

Sodium cholate hydrate is a bio-surfactant which can be used as a reducing reagent in aqueous solution.

Sodium cholate hydrate is a non-denaturing, anionic detergent.

アプリケーション

• Optimization in Transdermal Drug Delivery: Applied in the formulation of ultra-elastic nanovesicles, sodium cholate hydrate enhances the bioavailability and anti-inflammatory efficacy of deflazacort, demonstrating its potential in transdermal drug delivery systems, which can be adapted for diagnostic purposes (Ali et al., 2021).


• Nanocarrier Formulations for IVDs: The study utilizes sodium cholate hydrate in the surface modification of bilosomes, serving as a functional and biocompatible nanocarrier for hybrid compounds, a method applicable to the formulation of innovative IVD reagents (Waglewska et al., 2020).


• IVD Reagent Formulation for Skin Delivery: Sodium cholate hydrate is featured in the development of nano-transfersomes for the delivery of antioxidants, showcasing its role in creating skin-applied diagnostic reagents that offer antioxidant and anti-aging effects (Avadhani et al., 2017).


• Sorting and Separation Techniques in Nanotechnology: Demonstrating the affinity-mediated sorting order reversal, sodium cholate hydrate is critical in density gradient ultracentrifugation techniques, highlighting its utility in the precise sorting and preparation of materials for diagnostic assays (Jang et al., 2016).

安全性情報

• 危険有害性情報: H412
• 注意書き: P273 - P501
• 危険有害性の分類: Aquatic Chronic 3
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)