U1006

ウリジン 5′-三リン酸 三ナトリウム塩 溶液

HPLC purified, aqueous solution for RNA polymerase transcription

• 別名: UTP
• MDL番号: MFCD00044310
• UNSPSCコード: 41106305
• PubChem Substance ID: 24900622
• NACRES: NA.52

特性

• 由来生物: yeast (Candida Utilis)
• 品質水準: 300
• アッセイ: ≥95 (HPLC)
• フォーム: liquid
• 濃度: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• 色: colorless
• その他の活性: DNase and RNase, none detected
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• InChI Key: MMJGIWFJVDOPJF-LLWADOMFSA-K
• 遺伝子情報: human ... P2RY2(5029) ; rat ... P2ry2(29597)

詳細

アプリケーション

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

生物化学的／生理学的作用

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

法的情報

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable